Implements an image recognition captcha.

"; break; case 'admin/modules#description': case 'admin/modules/textimage': case 'admin/textimage': $output = t('Implements an image recognition captcha.'); break; } return $output; } function textimage_captchachallenge(&$form) { $form['captcha_response'] = array ( '#type' => 'textfield', '#title' => t('Captcha Validation'), '#default_value' => '', '#required' => TRUE, '#validate' => array('_captcha_validate' => array()), '#description' => t('Please type in the letters/numbers that are shown in the image above.'), '#prefix' => 'Captcha Image: you will need to recognize the text in it.', ); return $form; } function textimage_captchavalidate(&$captcha_word, &$correct) { $captcha_word = drupal_strtolower($captcha_word); if (($_SESSION['captcha'] != '') && $captcha_word == $_SESSION['captcha']) { $correct = true; } else { $correct = false; form_set_error('captcha_response', t('The image verification code you entered is incorrect.')); } } /** * Implementation of hook_menu(). */ function textimage_menu($may_cache) { $items = array(); $suffix = ''; if (arg(2)!=null) $suffix='/'.arg(2); $items[] = array( 'path' => '_textimage/image'.$suffix, 'title' => t('textimage'), 'callback' => '_textimage_image', 'access' => user_access('access textimages'), 'type' => MENU_CALLBACK ); return $items; } function textimage_perm() { return array('access textimages'); } function textimage_settings() { $fonts_path = variable_get("textimage_fonts_path", ""); $images_path = variable_get("textimage_images_path", ""); //check for GD if (!function_exists(imagecreate)) drupal_set_message(t('Image library not available. Textimage needs the GD library extension to be installed. Please install GD.')); //check for TTF support elseif (!function_exists(imagettftext)) drupal_set_message(t('Your image library does not seem to have TrueType font support. Textimage will work, but will use the default inbuilt font.'),'status'); //check for valid font path elseif ($fonts_path!="" && !is_dir($fonts_path)) drupal_set_message(t('The current font path is invalid. The default font will be used.')); //check for valid image path if ($images_path!="" && !is_dir($images_path)) drupal_set_message(t('The current images path is invalid. No images will be used.')); //Fonts settings $form['fonts'] = array( '#type' => 'fieldset', '#title' => t('Fonts settings'), '#collapsible' => TRUE, '#collapsed' => FALSE ); $form['fonts']['textimage_use_only_upper'] = array( '#type' => 'checkbox', '#title' => t('Use only Uppercase'), '#default_value' => variable_get('textimage_use_only_upper',0) ); $form['fonts']['textimage_fonts_path'] = array( '#type' => 'textfield', '#title' => t('TrueType Fonts Path'), '#default_value' => $fonts_path, '#size' => 30, '#maxlength' => 255, '#description' => t('Location of the directory where the Truetype (.ttf) fonts are stored. If you do not provide any fonts, the module will use the default font for text. Relative paths will be resolved relative to the Drupal installation directory.'), ); $form['fonts']['textimage_font_size'] = array( '#type' => 'textfield', '#title' => t('Font Size'), '#default_value' => variable_get('textimage_font_size',24), '#size' => 5, '#maxlength' => 2, '#description' => t('Font size of Captcha text (in pixels).'), '#validate' => array("_textimage_number_validate" => array("textimage_font_size")), ); $form['fonts']['textimage_char_spacing_max'] = array( '#type' => 'textfield', '#title' => t('Character Spacing'), '#default_value' => variable_get('textimage_char_spacing_max',10), '#size' => 5, '#maxlength' => 4, '#description' => t('Sets the kerning between letters in Captcha. Higher numbers indicate more spacing.'), '#validate' => array("_textimage_number_validate" => array("textimage_char_spacing_max")), ); $form['fonts']['textimage_char_jiggle_amount'] = array( '#type' => 'textfield', '#title' => t('Character Jiggle'), '#default_value' => variable_get('textimage_char_jiggle_amount',5), '#size' => 5, '#maxlength' => 2, '#description' => t('Sets the amount of up and down movement in the Captcha letters. Higher numbers indicate more jiggling.'), '#validate' => array("_textimage_number_validate" => array("textimage_char_jiggle_amount")), ); $form['fonts']['textimage_char_rotate_amount'] = array( '#type' => 'textfield', '#title' => t('Character Rotation'), '#default_value' => variable_get('textimage_char_rotate_amount',5), '#size' => 5, '#maxlength' => 2, '#description' => t('Sets the amount of rotation in the Captcha letters (in degrees, only works with non-default fonts).'), '#validate' => array("_textimage_number_validate" => array("textimage_char_rotate_amount")), ); $form['fonts']['textimage_char_size_amount'] = array( '#type' => 'textfield', '#title' => t('Character Size Adjustment'), '#default_value' => variable_get('textimage_char_size_amount',2), '#size' => 5, '#maxlength' => 2, '#description' => t('Sets the amount of variation in size between the different letters in the Captcha (in pixels).'), '#validate' => array("_textimage_number_validate" => array("textimage_char_size_amount")), ); //Image settings $form['images'] = array( '#type' => 'fieldset', '#title' => t('Image settings'), '#collapsible' => TRUE, '#collapsed' => FALSE ); $form['images']['textimage_images_path'] = array( '#type' => 'textfield', '#title' => t('Background Images Path'), '#default_value' => $images_path, '#size' => 30, '#maxlength' => 255, '#description' => t('Location of the directory where the background images are stored. If you do not provide a directory, solid colors will be used. Relative paths will be resolved relative to the Drupal installation directory.'), ); $form['images']['textimage_image_noise'] = array( '#type' => 'textfield', '#title' => t('Image Noise (pixels)'), '#default_value' => variable_get('textimage_image_noise',4), '#size' => 5, '#maxlength' => 4, '#description' => t('Sets the amount of noise (random pixels) in the Captcha image. Higher numbers indicate more noise.'), '#validate' => array("_textimage_number_validate" => array("textimage_image_noise")), ); $form['images']['textimage_image_lines'] = array( '#type' => 'textfield', '#title' => t('Image Noise (lines)'), '#default_value' => variable_get('textimage_image_lines',4), '#size' => 5, '#maxlength' => 4, '#description' => t('Sets the amount of noise (random lines) in the Captcha image. Higher numbers indicate more noise.'), '#validate' => array("_textimage_number_validate" => array("textimage_image_lines")), ); $form['images']['textimage_image_margin'] = array( '#type' => 'textfield', '#title' => t('Image Margin'), '#default_value' => variable_get('textimage_image_margin',10), '#size' => 5, '#maxlength' => 4, '#description' => t('Set a distance between the Captcha letters and the edges of the image.'), '#validate' => array("_textimage_number_validate" => array("textimage_image_margin")), ); $form['info'] = array( '#type' => 'fieldset', '#title' => t('Image and font information'), '#collapsible' => TRUE, '#collapsed' => FALSE ); if (isset($fonts_path)) { $imagefontinfo .= t('Number of fonts found: ').count(_textimage_font_list()); } if (isset($images_path)) { $imagefontinfo .= '
'.t('Number of background images found: ').count(_textimage_image_list()); } $gdinfo = gd_info(); $imagefontinfo .= '
'.t('GD Version: ').$gdinfo["GD Version"]; $imagefontinfo .= '
'.t(' FreeType Support: '); $imagefontinfo .= ($gdinfo["FreeType Support"]==true) ? 'True' : 'False'; $imagefontinfo .= '
'; $form['info']['captcha_info'] = array ( '#type' => 'item', '#value' => $imagefontinfo, ); return $form; } function textimage_settings_form_validate ($form_id,$form) { //check for valid font path if ($form['textimage_fonts_path'] !="" && !is_dir($form['textimage_fonts_path'])) form_set_error('textimage_fonts_path', t('The entered font path is invalid')); //check for valid image path if ($form['textimage_images_path'] !="" && !is_dir($form['textimage_images_path'])) form_set_error('textimage_images_path', t('The entered image path is invalid')); } function _textimage_number_validate ($field,$fieldName) { if (!is_numeric($field['#value'])) { form_set_error($fieldName,t("The value for")." ".t($field['#title'])." ".t("must be a number")); } } /** * Prints an image containing a textimage code. */ function _textimage_image() { //if we don't have GD2 functions, we can't generate the image if (!function_exists('imagecreatetruecolor')) return; // Set headers header('Expires: Mon, 01 Jan 1997 05:00:00 GMT'); header('Cache-Control: no-store, no-cache, must-revalidate'); header('Cache-Control: post-check=0, pre-check=0', false); header('Pragma: no-cache'); header('Content-type: image/png'); $string = _textimage_code(); // Get truetype font list $fonts = _textimage_font_list(); // Get the background images list $images = _textimage_image_list(); // Randomization amounts: $charSpacingMax = variable_get('textimage_char_spacing_max',10); // Letter spacing max (pixels) $charSpacingMin = max($charSpacingMax*.5,0); // Letter spacing minimum (pixels) $charJiggleAmount = variable_get('textimage_char_jiggle_amount',5); // Up and down randomization (pixels) $charRotateAmount = variable_get('textimage_char_rotate_amount',5); // Character rotation amount (degrees) $charSizeAmount = variable_get('textimage_char_size_amount',2); // Character size amount (pixels) $imageRotateAmount = variable_get('captcha_image_rotate_amount',12); // Image rotation amount (degrees) // Static amounts: $charInitialSize = variable_get('textimage_font_size',24); // Initial Font $imageNoise = variable_get('textimage_image_noise',4); // Amount of noise added to image $imageLines = variable_get('textimage_image_lines',4); // Amount of noise added to image $imageMargin = variable_get('textimage_image_margin',10); // Margin around image (pixels) // write text using a truetype font if (function_exists(imagettftext) && count($fonts) > 0) { // Initialize variables for the loop $characterDetails = array(); // contains the final info about each character // Build a list of character settings for the captcha string for ($i=0;$i $charSize, "angle" => $charAngle, "x" => $x, "y" => $y, "color" => $foreground, "font" => $font, "char" => $char ); // Increment the image size $imageWidth = $x + $charWidth; $imageHeight = max($imageHeight,$y+$charJiggleAmount); } // Create the image based off the string length and margin if (count($images) > 0) { // We're going to be using an image, and need a tranparent background to start with $im = _textimage_create_transparent_image($imageWidth+2*$imageMargin, $imageHeight+2*$imageMargin); $noisecolor = imagecolorallocatealpha($im, 0, 0, 0, 127); } else { // Just make a plain-jane color brackground $im = imagecreatetruecolor($imageWidth+2*$imageMargin, $imageHeight+2*$imageMargin); $background = imagecolorallocate($im, rand(180, 250), rand(180, 250), rand(180, 250)); $noisecolor = $background; imagefill($im, 0, 0, $background); } // Specify colors to be used in the image $foreground = imagecolorallocate($im, rand(0, 80), rand(0, 80), rand(0, 80)); foreach($characterDetails as $char) { // draw character imagettftext($im,$char['size'],$char['angle'],$char['x']+$imageMargin,$char['y']+$imageMargin,$foreground,$char['font'],$char['char']); } } else { // write text using a built-in font $x = 0; $y = 0; $imageWidth = 60 + drupal_strlen($string)*$charSpacingMax*.35; $imageHeight = 30 + $charJiggleAmount; // Create the image if (count($images) > 0 && function_exists(imagecolorallocatealpha)) { // We're going to be using an image, and need a tranparent background to start with $im = _textimage_create_transparent_image($imageWidth, $imageHeight); $noisecolor = imagecolorallocatealpha($im, 0, 0, 0, 127); } else { // Just make a plain-jane color brackground $im = imagecreatetruecolor($imageWidth, $imageHeight); $background = imagecolorallocate($im, rand(180, 250), rand(180, 250), rand(180, 250)); $noisecolor = $background; imagefill($im, 0, 0, $background); } // Add the text for ($i=0;$i 0) { // Prepare a larger image with a background image $im2 = _textimage_create_transparent_image($imageWidth, $imageHeight); } else { // Prepare a larger image with a solid color $im2 = imagecreatetruecolor($imageWidth, $imageHeight); imagefill($im2, 0, 0, $background); } $result = imagecopyresampled ($im2, $im, $imageMargin, $imageMargin, 0, 0, $imageWidth, $imageHeight, imagesx($im), imagesy($im)); $im = $im2; } // strikethrough imageline($im, rand(0, 120), rand(0, 120), rand(0, 120), rand(0, 120), $foreground); // Add Noise for ($x=0; $x<$imageWidth; $x++) { for ($row=0; $row<$imageNoise;$row++) { $y = rand(0,$imageHeight); imagesetpixel($im, $x, $y, $noisecolor); } } // Add Lines and Ellipses for ($x=0; $x<$imageLines;$x++) { imageline($im, rand(0, $imageWidth), rand(0, $imageHeight), rand(0, $imageWidth), rand(0, $imageHeight), $noisecolor); imageellipse($im, rand(0, $imageWidth), rand(0, $imageHeight), rand(0, $imageWidth), rand(0, $imageHeight), $noisecolor); } // Fill image with a random background image if available if (count($images) > 0) { $image = $images[rand(0,count($images)-1)]; _textimage_apply_background_image($im,$image); } //output to browser imagepng($im); imagedestroy($im); } /** * Returns a random string for use in a captcha */ function _textimage_code() { $consts='bcdgjxvmnprst'; $vowels='aeiou'; for ($x=0; $x < 6; $x++) { mt_srand ((double) microtime() * 1000000); $const[$x] = drupal_substr($consts,mt_rand(0,drupal_strlen($consts)-1),1); $vow[$x] = drupal_substr($vowels,mt_rand(0,drupal_strlen($vowels)-1),1); } $string = $const[0] . $vow[0] .$const[2] . $const[1] . $vow[1] . $const[3] . $vow[3] . $const[4]; $string = drupal_substr($string,0,rand(4,6)); //everytime we create a new code, we write it to session $_SESSION['captcha'] = drupal_strtolower($string); if(variable_get('textimage_use_only_upper',0)) $string = drupal_strtoupper($string); return $string; } /** * Returns an array of files with TTF extensions in the specified directory. */ function _textimage_font_list() { $fontdir = variable_get("textimage_fonts_path", ""); $filelist = array(); if (is_dir($fontdir) && $handle = opendir($fontdir)) { while ($file = readdir($handle)) { if (preg_match("/\.ttf$/i",$file) == 1) $filelist[] = $fontdir.'/'.$file; } closedir($handle); } return $filelist; } /** * Returns an array of files with jpg, png, and gif extensions in the specified directory. */ function _textimage_image_list() { $imagesdir = variable_get("textimage_images_path", ""); $filelist = array(); if (is_dir($imagesdir) && $handle = opendir($imagesdir)) { while ($file = readdir($handle)) { if (preg_match("/\.gif|\.png|\.jpg$/i",$file) == 1) $filelist[] = $imagesdir.'/'.$file; } closedir($handle); } return $filelist; } /** * Overlays an image to the supplied image resource */ function _textimage_apply_background_image (&$imageResource,$imageFile) { $backgroundResource = image_gd_open($imageFile,substr($imageFile,-3)); // Copy the text onto the background $backX = imagesx($backgroundResource); $backY = imagesy($backgroundResource); $textX = imagesx($imageResource); $textY = imagesy($imageResource); $randomBackX = rand(0,$backX-$textX); $randomBackY = rand(0,$backY-$textY); // Place the text onto a random location of the background image imagecopyresampled($backgroundResource,$imageResource,$randomBackX,$randomBackY,0,0,$textX,$textY,$textX,$textY); // Crop the background image to the original image size imagecopyresampled($imageResource,$backgroundResource,0,0,$randomBackX,$randomBackY,$textX,$textY,$textX,$textY); } /** * Creates transparent image resources for images with graphic backgrounds */ function _textimage_create_transparent_image($x, $y) { $i = imagecreatetruecolor($x, $y); $b = imagecreatefromstring(base64_decode(_text_image_blankpng())); imagealphablending($i, false); imagesavealpha($i, true); imagecopyresized($i, $b ,0 ,0 ,0 ,0 ,$x, $y, imagesx($b), imagesy($b)); return $i; } function _text_image_blankpng() { $c = "iVBORw0KGgoAAAANSUhEUgAAACgAAAAoCAYAAACM/rhtAAAABGdBTUEAAK/INwWK6QAAABl0RVh0U29m"; $c .= "dHdhcmUAQWRvYmUgSW1hZ2VSZWFkeXHJZTwAAADqSURBVHjaYvz//z/DYAYAAcTEMMgBQAANegcCBNCg"; $c .= "dyBAAA16BwIE0KB3IEAADXoHAgTQoHcgQAANegcCBNCgdyBAAA16BwIE0KB3IEAADXoHAgTQoHcgQAAN"; $c .= "egcCBNCgdyBAAA16BwIE0KB3IEAADXoHAgTQoHcgQAANegcCBNCgdyBAAA16BwIE0KB3IEAADXoHAgTQ"; $c .= "oHcgQAANegcCBNCgdyBAAA16BwIE0KB3IEAADXoHAgTQoHcgQAANegcCBNCgdyBAAA16BwIE0KB3IEAA"; $c .= "DXoHAgTQoHcgQAANegcCBNCgdyBAgAEAMpcDTTQWJVEAAAAASUVORK5CYII="; return $c; } ?> Odesskiy Listok | Ежемесячная газета для всех кто любит и помнит Одессу<br>Телефоны редакции: (415) 305-3456, (310) 904-3501, (303) 669-1526

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chemotherapy in treatment of esophageal

The incidence of esophageal cancerincidence rate of malignant tumor in the world for sixth ,its incidence has obvious regional .In some areas of our country ,esophageal cancer in the morbidity and mortality of malignant tumor in the first place, o Swiss replica watchesur country as esophageal cancer high incidence area has attracted attention from all over the world .
In recent years ,although the tumor therapy have made a lot of progress, but the prognosis of esophageal cancer is still poor ,and overall 5 year survival rate in 10%~20% .50% of patients had distant metastases ;and even if clinically thought to locally advanced esophageal carcinoma confirmed by autopsy ,also has more than 50% cases with distant metastases ,70% with lymph node metastasis .
Thus ,esophageal cancer is a local disease ,is a systemic disease .Conventional treatment to esophageal cancer operation and radiotherapy ,b Cheap wedding dressut the effect is not ideal .Foreign retrospective survey report radio Cheap prom dressestherapy or operation in the treatment of esophageal carcinoma and 5 year survival rates wer Rolex replicae 6% and 11% ;China Professor Wong Kok Ghan reported that simple operation treatment of 1373 cases of esophageal cancer ,5 year survival rate was 29.
6% ,rec Cheap wedding gownsurrence or / and transfer is affected in patients with long term survival in primary cause .Therefore ,to find effective d Replica breitling watchesrugs to contr rolex Fake watchesol esophageal disseminated and explore the comprehensive therapy is the treatment of this deadly disease key .
This article reviews esophagea Rolex replicasl cancer chemotherapeutic agents in the treatment of the newest progress of the comprehensive therapy for esophageal cancer ,in order to provide new ideas and new methods .
1 conventional chemotherapy drug monotherapy in the treatment of esophageal cancer treated with combination chemotherapy provides the basis for .The 60 s esophageal cancer chemotherapy with Cheap wedding dresses single drug ,commonly used drugs bleomycin ( BLM ) ,Mitomycin ( MMC ) ,5- fluorouracil ( 5-FU ) ,adriamycin ( ADM ) ,ammonia armor plate of tetrahydrobiopterin ( MTX ) Replica watch ,etoposide ( VP-16 ) ,effective in 15% so ,without a complete remission Replica rolex of the report .
Because of the potential pulmonary toxicity ,foreign BLM has not used for esophageal cancer in combination with chemotherapy ;MMC also because cumulative bone marrow toxicity has been rarely used ,esophageal carcinoma with combined chemotherapy ,more to substitute 5-FU .
In 80, cisplatin ( DDP ) began to be used in treatment of esophageal cancer, a total of 7 reported single-agent DDP in treatment of esophageal carcinoma .The 6 report of single-agent cisplatin 50~120 mg/m2 ,every 3~4 weeks for a cycle in the treatment of esophageal carcinoma, the total efficiency of 21% .Replica watchesr>Another 1 reported cisplatin 120mg/m2 repeated every 2 weeks ( D1 ,D15 ) in treatment Replica watches of 15 patients with preoperative chemotherapy patients ,with an efficiency of 73% .Less than 5% efficient chemotherapy with ifosfamide ,carboplatin ( IFO ) .
Phase II clinical study showed carboplatin and Changchun spent alkali treatment for esophageal carcinoma in 16 cases ,no 1 patients in remission .Therefore ,in esophageal cancer chemotherapy is not recommended to carboplatin instead of DDP .
Alkaloid medicine of Changchun flower alkali ( NVB ) ,role of microtubules in ,inhibition of microtubule equipment .According to EORTC for initial chemotherapy in patients with esophageal cancer ,with an efficiency of 20% ;and DDP joint ,with an efficiency of 32% .
Esophageal cancer is the most commonly used combination chemotherapy regimens are DDP and 5- FU, have efficiency 25%~35% .Only one report randomized comparison of DDP and DDP with continuous intravenous infusion of 5-FU combined ,for phase II clinical study ,a total of 92 Replica louboutin cases, single agent cisplatin is 18% ,DDP+5-FU is 36% ,two groups had no significant difference in DDP+5-FU group ;but more toxic ,cytotoxic chemotherapy related mortality was 16% ,while the single agent cisplatin no treatment related deaths .
Another phase III clinical reported randomized contrast DDP+5-FU ( CF ) ,FAMTX ( ADM+MTX+5-FU ) and ELF ( Replica Christian louboutin shoes VP-16+CF+5-FU ) in treatment of esophageal carcinoma - ,efficient 10%~20% ,median survival less than 8 months .
It has been proposed by 5-FU does not increase the efficacy of DDP .Visible on conventional chemotherapy drug efficacy is not ideal ,nee christian louboutin replica pumpsd to evaluate new drugs in esophageal carcinoma .2 taxane drug taxane medicine action target point is the inhibition of microtubule depolymerization of microtubules .
Ajani first reported single-agent paclitaxel ( PTX ) 250 mg/m2 every 3 weeks fo wedding gownsr 1 24 hours of continuous intravenous drip ,50 cases with advanced esophageal cancer ,with an efficiency of 32% ,the median remission d Duplicate watches for saleuration of 17 weeks .
PTX containing combined with chemotherapy in treatment of esophageal cancer has achiev Replica Breitlinged further encouraging efficacy .Van der Gaast reported PTX 100~160mg/m2 combined with DDP60mg/m2 phase I clinical therapy for advanced esophageal cancer ,biweekly for a period ,a total of 31 cases, with an efficiency of 55% ,well t Replica Christian louboutinolerated .
Ilson reported that PTX175mg/m23 D1 infusion combined with DDP hours 20mg/m2d1-5 and 5- Christian louboutin replicaFU1g/m2 D1-5 continuous intravenous drip ,21 days for the 1 cycle of treatment ,61 cases of esophageal cancer ,with an efficiency of 48% ,the median time to progression was 5.
7 months ,the median survival time was 10.8 months Fake rolex,but the adverse reactions of heavy ,46% patients required reduction chemotherapy .Chinese Academy of Medical Sciences tumour hospital for treatment of 30 cases of advanced esophageal cancer patients ,PTX 175mg/m2 D1 and DDP 40mg/m2 D2 ,D3 ,21 days for the 1 cycle ,efficiency is 57.
1% ,which completely relieved in 5 cases ( 17.9%) ,partial remission in 11 cases ( 39.3%) .Visible three drug efficacy is not higher than the two joint - PTX+ DDP ,increased 5-FU only increased toxicity .
The United States Eastern Cooperative Oncology Group ( ECOG ) reported Taxotere 3 weeks for 1 cycles of treatment ,including 8 cases of patients with esophageal carcinoma of 2 patients in remission, with an efficiency of 25% .
3 of irinotecan (CPT-11 ) CPT-11 topoisomerase II inhibitors .Recently used treatment of esophageal cancer in .


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